Nadia Anwar
Research
- .
- I am Research Scholar at the Memorial Sloan Kettering Cancer Centre in New York, working on the BioPAX pathway exchange model and Pathway Commons.
Post Docs
Interfacing proteomic and genomic data. Post Doc in the RASOR project. I was tasked to implement technologies to interface across proteomic and genomic data. The focus of this project is improved data handling, storage and distribution through an integrated LIMS systems as a foundation to the establishment of an integrated relational database. On the face of it, this is classic data integration of two heterogeneous data systems, however, given the nature of the data sources, proteomics data and genomics data, actual integration would be minimal since the overlapping data elements are few. The data are semantically different and therefore not only are they difficult to physically integrate but the process would add little value to the data itself. Since the actual reason for integration is to query the data as a unit, it is more important to the data users to have the data in a form that allows querying across these data. Semantic integration promises to provide exactly this capability. I am using RDF, RDF-S and OWL to integrate genomic, proteomic and transcriptomic data.
PhD
The problem my PhD studies addressed was the use of different hierarchies in information retrieval. Different opinions in taxonomic placement has meant that different taxonomic resources, such as NCBI and ITIS, use different taxonomic hierarchies. While it is very useful to conduct a hierarchical search to retrieve data, for example all Insecta data or all data in the genus Drosophila, in practice this is difficult because the term Insecta in one taxonomic resource can contain very different data in another. Enabling hierarchical queires in systems such as TreeBASE is therefore a challenge that requires delivering and maintaining taxonomic hierarchies that encompasses current taxonomic opinion.
TCl-Db is a datawarehouse of taxonomic names and classfication hierarchies that can be layered over systems such as TreeBASE to enable hierarchical queries.
TCl-DB TreeBASE wrapper can be found here.
Contact
E-MAIL: anwarn @ mskcc . org
SKYPE: anwarnadia
Publications/Presentations
BMC Bioinformatics 2009, 10(Suppl 10):S3 (1 October 2009)
Nadia Anwar and Ela Hunt
[Abstract][PDF]
BMC Evolutionary Biology 2009, 9:93 (8 May 2009)
Nadia Anwar and Ela Hunt
[Abstract][PDF]
Semantic Web Applications and Tools for Life Sciences (SWAT4LS), November 2008, Edinburgh, Scotland.
Nadia Anwar, Ela Hunt, Walter Kolch and Andrew Pitt
N. Anwar
PDF (9.5M)
Workshop on Database Issues in Biological Databases (DBiBD), January 2005, Edinburgh, Scotland.
N. Anwar
DBiBD Proceedings
3rdEuropean Conference on Computational Biology (ISMB/ECCB2004)
August 2004, Glasgow, Scotland.
Poster - Taxonomy, Biology's first ontology, and the Tree of Life, Biology's grandest endeavour.
N. Anwar